Nutrition and nutrients: daily single cups of coffee for 50% risk of primary liver cancer can occur, according to a study among about 100,000 Japanese period of ten years.

23 February 2005: source: Nutraingredients

A few cups of coffee per day reduces the risk of primary liver cancer with approx. 50% epidemologische under study shows 100,000 Japanese adults over a period of ten years. Striking has always been that primary liver cancer in Asia is much more common than in Western countries. As far as we know is also much more coffee than in Western countries in Asian countries. Maybe it is to establish a link. Who reads these articles under liver cleansing under koffieklisma see that a on his time also for lighting can bring in people with liver tumors. Or here link exists between coffee enemas or to use to help in other ways to use enemas to say but what we dare not let u if you still performs regularly for coffee enemas to use. Please always do this under expert guidance you can Different orthomolecular doctors , though not everyone in it is easily accompany specialized. So ask this at the consulted doctor well after that you specifically want information and guidance about enemas. Here first the abstract of the study and then the article from Nutraingredients about this study.

J. Natl. Cancer Inst. 2005 Feb 16; 97 (4): 293-300.

Influence of coffee drinking on subsequent risk of hepatocellular carcinoma: a prospective study in Japan.

Sobue T, Inoue M, Yoshimi I, Tsugane S; JPHC Study Group.

Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045 Japan. mnminoue@gan2.res.ncc.go.jp

BACKGROUND: An association between coffee drinking and reduced risk of liver cancer has been suggested by animal studies, but epidemiologic evidence of such an association in a high-risk population is lacking. We conducted a large-scale population-based cohort study of the association between hepatocellular carcinoma (HCC) in coffee drinking and a Japanese population.

METHODS: Newly diagnosed case patients (250 men and 84 women) with HCC were identified from a 10-year follow-up of the Japan Public Health Center-based Prospective Study, which consists of middle-aged and elderly Japanese subjects 90,452 (47,343 men and women 43,109). Case patients were grouped according to coffee intake and were stratified by hepatitis virus infection, sex, age, diet, lifestyle factors, and previous history of liver disease. -Adjusted hazard ratios (HR) and Multivariable 95% confidence intervals (CIs) were calculated with Cox proportional-hazards for HCC modeling. All statistical tests were two-sided.

RESULTS: Subjects (men and women combined) who consumed coffee on a daily or almost daily basis had a lower HCCrisk than those who almost never drink coffee (HR = 0.49 [95% CI = 0.36 to 0.66]); risk decreased with the amount of coffee consumed (compared with nondrinkers, the HR for 1-2 cups per day = 0.52 [95% CI = 0.38 to 0.73]; for 3-4 cups per day = 0.48 [95% CI = 0.28 to 0.83]; for 5 cups per day = 0.24 > or = [95% CI = 0.08 to 0.77], P (trend)< .001).="" the="" risk="" of="" liver="" cancer="" in="" almost="" never="" drinkers="" in="" this="" population="" was="" 547.2="" cases="" per="" 100,000="" people="" over="" 10="" years,="" but="" it="" was="" 214.6="" cases="" per="" 100="" 000="" people="" with="" drinking="" coffee="" on="" a="" daily="" basis.="" the="" inverse="" association="" persisted="" when="" the="" participants="" were="" stratified="" by="" lifestyle="" factors.="" similar="" associations="" were="" observed="" when="" the="" analysis="" was="" restricted="" to="" hepatitis="" c="" virus-positive="" patients="" (all="" daily="" drinkers="" compared="" with="" nondrinkers:="" hr="0.57" [95%="" ci="0.37" to="" 0.86]),="" to="" hepatitis="" b="" virus-positive="" patients="" (hr="0.60" [95%="" ci="0.31" to="" 1.18])="" and="" to="" subjects="" with="" no="" past="" history="" of="" chronic="" liver="" disease="" (hr="0.45" [95%="" ci="0.30" to="">

CONCLUSIONS: In the Japanese population, habitual coffee drinking may be associated with reduced risk of HCC.

PMID: 15713964 [PubMed-in process]

Nutraingredients article from here:

16/02/2005-benefits and risks of coffee drinking on consumer health are the focus of two new studies that ultimately reveal the positive, or negligible impact, of this popular beverage. One study found that daily drinking coffee could cut the risk of liver cancer, while the other found no association between drinking coffee or tea, and the risk of colorectal cancer. Coffee consumption is common throughout the world, with retail sales hitting about € 54 billion. And scientists continue to explore the impact it may have on human health. The first study, published in the February 16 issue of the Journal of the National Cancer Institute, found that people who drink coffee on a daily or almost daily basis had about half the risk of developing hepatocellular carcinoma (HCC: a type of liver cancer) compared with those who never drink coffee. According to researchers at the National Cancer Center in Tokyo that carried out the study, the rate of liver cancer among those who never drink coffee cases per 100,000 people was 547.2 over 10 years. Among daily coffee drinkers the rate was almost fifty per cent less, at about 100,000 cases per 214.6 people. Of particular interest, the risk of HCC decreased with an increase in the amount of coffee consumed each day. But the authors caution that because decaffeinated coffee is rarely consumed in Japan, and therefore no distinction was made between caffeinated and decaffeinated coffee, they were unable to determine if caffeine was responsible for the decreased risk of HCC. "Further studies are warranted to assess whether the present results can be generalised or are representative of other populations," say the researchers. In the second study, Karin b. Michels andcolleagues at Brigham and women's Hospital in Boston, explored the association between coffee, tea, and caffeine consumption and the incidence of colorectal cancer. They used data from two large prospective studies (the Nurses ' Health Study (women) and the Health Professionals ' follow-up Study (men)), that totalled almost 2 million person years of follow-up. The researchers report that they found no association between consumption of caffeinated coffee or tea and the incidence of colon or rectal cancer in either group. But suggesting the benefits of study participants who regularly drink decaff consumption, two or more cups per day or decaffeinated coffee, had about half the incidence of rectal cancer compared with those who never drink decaffeinated coffee. The authors caution that this observed association may be due to differences in lifestyle; because coffee might be more health conscious drinkers or decaffeinated in their behaviour than those who consume caffeinated coffee. They recommended new studies to confirm the vesus caffeine decaffeinated findings. After being dogged by poor prices in recent years following a glut in coffee production, prices are just starting to recover for the global industry. A surge in Arabica prices recorded during the last quarter of 2004 continued into January 2005. According to the International Coffee Organisation, most of January's Arabica transactions involved pricelevels US107 cents/lb or about 70 cents/lb compared to below US a year ago.