CANCER.

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Diagnosis of colorectal cancer - colonoscopy miss very often (approx. 42%), cancer of the appendix (appendix and appears unreliable for diagnosis of cancer. Article posted December 22, 2008

December 22, 2008: Source: 1: J Gastrointest Surg. 2008 in December 1917.

Cancer (type adenocarcinoma) of the appendix (appendix) is rarely detected by colonoscopy in people who have complaints that seem to indicate colon cancer. This emerges from a study of 121 cancer patients in the period 1993 to 2007 were all treated for cancer in the. Only a few cancer patients had the colonoscopy for further investigation or to refer a treatment for colon cancer. A stool test and / or blood test (FOB or IOBT) seems much more accurate, although this study does not indicate or are too early cancer of the appendix can be detected.

Adenocarcinoma of the appendix Is Rarely Detected by Colonoscopy.

Trivedi AN , EA Levine , G Mishra .

Section of Gastroenterology, Wake Forest University Baptist Medical Center, Medical Center Blvd, Winston-Salem, NC, 27157, USA.

INTRODUCTION: Appendiceal tumors represent a subset of colonic neoplasms frequently That Defy early diagnosis only to present at advanced stage with Peritoneal metastasis. Data on early detection by colonoscopy is limited to case reports or series. The AIM of this study is to determining the diagnostic yield of colonoscopy in detecting lesions in patient with appendiceal appendiceal adenocarcinoma and Pseudomyxoma peritonei.

METHODS: We reviewed clinicopathologic data on 121 Consecutive Patients with histologically CONFIRMED Pseudomyxoma peritonei with appendiceal adenocarcinoma presenting to our institution for intraperitoneal hyperthermia chemotherapy (IPHC) and cytoreductive surgery Between February, 1993 and August, 2007, focusing on the colonoscopy findings.

RESULTS: Preoperative colonoscopic Were data available on 64 patients (average age = 51; 52 patiënten for IPHC). Abnormal Findings included seven patiënten with appendiceal lesions (11%), 12 patients with cecal abnormalities (19%), and 28 patients with polyps (44%). Twenty-three patients (36%) had a normal colonoscopy. Documented malignancy was in two of the 64 (3.1%) patients on Preoperative colonoscopy biopsies.

CONCLUSIONS: Appendiceal abnormalities are infrequently seen on colonoscopy and biopsy Rarely yield a diagnosis in patient with appendiceal carcinoma. We found That Nearly 42% of Patients with carcinoma of the appendix have synchronous colonic polyps, a much higher prevalence Than Would be expected, supporting a role for a perioperative colonoscopy.

PMID: 19089515 [PubMed - as supp song by publisher]