Esophageal cancer would be faster and more accurate at detecting a fluorescent spray and can thus sometimes burdensome through operations be prevented. Article update 1 February 2012
28 January 2012: source: Mailonsunday
English researchers at Cambridge University have developed a high visibility throat spray to detect esophageal cancer earlier and better able to determine where the tumor is and how far it has spread.The current methods used for detecting and can be so inaccurate or lat diagnosteren done that part of the patients an unnecessary and excessive invasive treatment including removal of their esophagus.
Now scientists have developed a high visibility dye spray that attaches itself to healthy cells in the esophagus, but who are not can attach to cancer cells. If this spray is used gives this a clear reference to the place where the tumor develops.If at this stage can be spotted, budding tumors cancer cells to be removed with a form of RFA-Radio Frequency Ablation.
Lead researcher Dr. Rebecca Fitzgerald says: "the current methods for screening on esophageal cancer are controversial-they are expensive, uncomfortable for the patient and are not completely accurate.Our technique highlights the exact position of an evolving esophageal cancer and how far it has spread. And gives a more accurate picture than other techniques.
With this method, researchers have been able to preventat some patients from the study group that this should be a major operation.
The researchers tested this treatment at 80 biopsies of people with the disease of Barrett (reflux), a condition that increases the risk of esophageal cancer. And they tested the method on four patients with esophageal cancer.
The researchers say that the dye used is relatively cheap and probably cause few side effects because it uses a kind of wheat germ protein that exists in our normal nutrition.
This dye binds to Glycans-sugar molecules-on the surface of cells in the esophagus and the researchers add a fluorescent tag to let it out on green lights under the light of a specific wavelength.
The whole can then be viewed using an endoscope.
The show exactly where all small changes take place Glycans in the fabric. Changes that with other methods not be traced.
Before the spray can be used there will be multiple studies should be done with larger groups of patients, but the researchers expect that within 5 years this method will be available for general use.
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