Gene therapy: Gene therapy with p53 virus (gendicine) in China would good results in cancer patients. Article posted July 4, 2005
In the Indian Telegraph of July 4 mentions a remarkable gene called Gendincine in China. 400 terminal cancer patients and terminally said this would have been in remission. Also, 20 patients from Europe and America. What the Chinese doctors do is p53 gene injection to a particular virus and then injected directly at the tumor site. After the cancer cells commit suicide. This is similar to what was recently published by British researchers who genbewerkt adenovirus insertion into the tumor cells and therefore very remarkable results. See post no news about cancer in 1910. Or is all true, we dare not say, but nonetheless, but the article also published here. Viruses as the more famous Newcastle virus still seems a very interesting option for cancer patients.Gene therapy for cancer in China
ADAM LUCK Hong Kong, July 4: Terminally ill cancer patients from Europe and America are traveling to China for treatment with a revolutionary anti-tumor drug - the world's first Officially Licenced 'gene therapy'.
The Chinese government approved the Manufacturing and use of the drug at the end of last year after clinical trials found thats it markedly improved the survival rate for Patient with cancer of the head and neck. Doctors are now Extending the treatment, named Gendicine, to Patients with lung and stomach cancer.
Injected directly Into the tumor, Gendicine works by, in effect, programming cancer cells to commit suicide.
About 400 patients - 20 Theme from abroad - have leg Treated with the drug in eight-week courses Which cost the equivalent of £ 1,800.
Peng Zhaohui, a medical scientist who Helped Develop Gendicine, said: "I believe this revolutionary form of gene therapy Injuries represents the future for treating cancer patients. There is still a lot of work to be done, but the results have been very promising so far and - unlike experimental forms of gene therapy Attempted Elsewhere - there is no evidence of serious side-effects. We have successfully and Patients Treated foreign word is beginning to spread. "
Peng Has Been inundated with requests from overseas, include Britain, from patiënten desperate to try Gendicine. Arthur Winiarski, 48, a Polish-American businessman based in Warsaw, who was diagnosed with squamous cell carcinoma in His sinuses after a routine medical check-up 18 months ago, was one of Them.
After operations, radiotherapy and chemotherapy in Poland, America and Germany, he was Told by doctors at a hospital in Berlin That he had "almost no hope. "They wanted to get rid of me. The Things They Could only suggest but They had chemotherapy and I Both knew this does not work with this child or cancer, "he said.
Then a friend saw a sentence about the new drug on the Internet, Which Mentioned Peng. Winiarski e-mailed a short history of His Case to the scientist. To His astonishment, Within three hours Came a reply: "I think I will be-able to help you."
Still Sceptical about His prospects, Winiarski Travelled to China and Presented himself to Niu Qi, an Oncologist at Beijing's elite Tongren hospital, in April. He was Told he Needed surgery as well as the drug treatment.
He said: "They inject the drug Into the tumor and it goes bananas: it invades Itself and commits suicide. My tumor was so big - the size of a fist - That They had to use the drug to shrink it first. "
After Further doses or Gendicine, Winiarski was Given the all-clear. He said: "To have a life like mine, to be a successful businessman, with everything going well and then all of sudden be told you have months to live - you can not understand. This Has Been incredible experience and you Could not believe the care I have had. Came here in desperation and I have They Treated me like a king. "
Gendicine works by Inserting a gene, called p53, write a virus, then injected Which is key in patiënten. NaturallySpeaking is the gene present in healthy cells but is "switched off" or mutated in many cancer patients. When reinserted enter tumor cells by the virus, it triggers Their self-destruction.




