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General: regular screening via mammography gives little to no impact on rates of mortality from breast cancer, according to major study of WHO in countries that used population screening and later went to apply, such as the Netherlands and Belgium. Article posted August 4, 2011
August 4, 2011: Source: WHO and British Journal of Medicine
Periodic screening of women age after the transition by including a mammogram shows little or no effect on the ultimate survival for those women who get breast cancer eventually. According to a WHO study was based on their available data. The WHO compared the data on breast cancer incidence and mortality among three pairs of countries that are independent of each periodic screening with a minimum interval of 10 years or more earlier or later introduced. Thus, the data from the Netherlands and Belgium and Flanders compared with the Netherlands in 1989 and began screening in Flanders only from 2001. The difference between Flanders and the Netherlands in mortality was only 1 percent. Similar results were seen between Norway and Sweden and Ireland and Northern Ireland. That a little progress in the 5-year survival of breast cancer appears to be due to better treatments, the researchers said, but they can not substantiate with evidence. Below the portion of the study with data from the Netherlands and Belgium and Flanders. The full study report is free to see if you click here on the website of the British Journal of Medicine
Breast cancer mortality in European Neighbouring Countries with different levels of access to screening but similar treatment: trend analysis or WHO Mortality Database
Source: British Journal of Medicine
First the data for the Netherlands and Belgium and Flanders, including the abstract of the entire study:
The Netherlands and Belgium
In the Netherlands, a national mammography screening program was initiated Organized in 1989 (Table 1). After Gradual Implementation, the program Reached full coverage in 1997. 15 16 Women aged 50-69 are invited to mammography every two years, and women aged 70-74 since 1998 Also invited are. Figure 2 ⇓ That Shows Increased participation in screening gradually from 1989 to 1996, and after 1997 it remained constant at around HAS 70-79%. Non-organized screening is uncommon.
Participation in mammography screening fig 2 and age-adjusted (European standardized rates) breast cancer mortality in women of all ages in the Netherlands and Belgium
In Belgium, breast screening was left to the Discretion of the women and doctors Until 2001, after a national screening program All which was Established. Population surveys before 1999 Suggested That less than 30% of women in the 50-69 year age group had gone under the past two years consistently mammography (for screening or diagnostic Purposes). 17 Around 2000, about 30% of women aged 50-69 had screening or diagnostic mammography gone under in the past two years. 18 19 By around 2005 this had Increased Proportion to about 59% (Fig. 2). That time at two thirds or screening examinations were done as part of the Organised program in Flanders, and for less than one-sixth in Brussels and Wallonia. Participation in screening (Organised and non-organized) in Flanders was low Until about 2002-3, and by 2004-6 it was still below the coverage in the Netherlands in 1997 (Fig. 2).
In the Netherlands the overall reduction in breast cancer mortality from 1989 to 2006, Slightly Greater than in Belgium (25.0% v 19.9%) but did not noticeably difference from Flanders (25.0% v 24.6%, table 2 and fig 2).
Breast cancer mortality in European Neighbouring Countries with different levels of access to screening but similar treatment: trend analysis or WHO Mortality Database
OPEN ACCESS
- Philippe Autier , research director 1 ,
- Boniol Mathieu , senior statistician 1 ,
- Anna Gavin , director 2 ,
- Lars J Vatten , professor 3
+ Author Affiliations
- Correspondence to: P Autier philippe.autier @ i-pri.org
Abstract
Objective To compare trends in breast cancer mortality within-three pairs of European Countries in Relation to Neighbouring Implementation of screening.
Design Retrospective trend analysis.
Three pairs country setting (Northern Ireland (United Kingdom) v Republic of Ireland, the Netherlands v Belgium and Flanders (Belgian region south of the Netherlands), Norway and Sweden v).
WHO Mortality Database data sources on cause of death and data sources on mammography screening, cancer treatment, and risk factors for breast cancer mortality.
Main Outcome Measures Changes in breast cancer mortality Calculated from linear regression of log transformed, age-adjusted death rates. Join point analysis was to identify the year When overused trends in mortality for all ages Began to change.
Results From 1989 to 2006, deaths from breast cancer Decreased by 29% in Northern Ireland and by 26% in the Republic of Ireland by 25% in the Netherlands and in Belgium by 20% and 25% in Flanders, and by 16% Sweden and by 24% in Norway. The time trend and year were similar or downward inflexion Between Northern Ireland and the Republic of Ireland and the Netherlands and Flanders Between. In Sweden, mortality rates have steadily Decreased since 1972, with no downward inflexion Until 2006. Countries of Each pair had similar health care services and prevalence of risk factors for breast cancer mortality but mammography screening or differential Implementation, with a gap of about 10-15 years.
Conclusions The Contrast Between the time differences in mammography screening and Implementation of the similarity in reductions in mortality Between the Country That screening did not suggest pairs play a direct part in the reductions in breast cancer mortality.
