Scientific research on nutrition and natural approaches and resources in cancer. Studieabstracten study and analysis.
Here we list articles and studies or research on cancer in relation to nutrition. With some additional comments other as we found on the Internet. We will complement these articles regularly, but that takes time and we want very carefully. We have tried to research and articles in logical and more or less alphabetical order. Often an article in the name of nutrient - vitamin etc. But sometimes in diets or diet in cancer or cancer type out the first named, including bladder cancer and vitamins in the BA. So take the name of one nutrient or use search to start because of various cancers are also often important studies and articles that are not all in this list.
If there are people who can give us tips like please send us remarkable investigations and we post on the site. (See also reading list ( This list compiled by physician-biologist Erik Valstar has exceeded 1500 and are all randomized trials) and cancer rates ). In addition, a recommendation to information on proven effects of diet and nutritional supplementation in cancer of the book: Nutritional intervention in cancer, a signal to the conventional oncology. Because physician-biologist Dr Engelbert Valstar. The book costs 16.95 and the ISBN number is 90 5860 192 7.
Capsaicin ointment (dust is common in red peppers) externally applied, significantly reduces neurological pain (nerve pain) caused by surgery in cancer patients in randomized placebo-controlled phase III study, already published in 1997. Article posted on April 10, 2006.
April 10, 2006: Source: J Clin Oncol. August 1997, 15 (8) :2974-80.Capsaicin cream, (the fabric is capsaicin in red peppers and chilies that makes them as hot / sharply perceived) appears highly significant neurological pain (neuralgia) in cancer patients who undergo surgery for their cancer. We translated the abstact of this study, already in 1997 !!!!! was published. See positive effects from using capsaicin in prostate cancer itself: Capsaicin is a substance that is common in red peppers = promotes apoptosis of prostate cancer cells commit suicide.
Phase III placebo-controlled trial of capsaicin cream in the treatment of surgical neuropathic pain (nerve pain) in cancer patients.
Ellison N, Loprinzi CL, Kugler J, Hatfield AK, Miser A, Sloan JA, Wender DB, Rowland KM, Molina R, Cascino TL, Vukov AM, Dhaliwal HS, Ghosh C.
Geisinger Clinical Oncology Program, Danville, PA, USA.
OBJECTIVE: A minority of cancer survivors develop post-operative (after surgery) and long-term nerve pain. Based on the evidence that capsaicin, the sharp / hot ingredient in hot chili peppers, could be useful in treating nerve pain, we designed this clinical trial.
PATIENTS AND METHODS: 99 eligible patients with postoperative nerve pain were admitted to this study. After stratification (division into groups), patients were given 8 weeks long capsaicin cream (0.075% capsaicin content) followed by 8 weeks of two similar placebo cream, or vice versa. The capsaicin / placebo ointment four times a day on the sore spots greased. Evaluation of the treatment was performed by weekly questionnaires filled out by patients.
RESULTS: During the first 8-week period, the capsaicin ointment administration was associated with substantially more skin burning, skin redness and coughing (P <.0001 for leaks). However, treatment with capsaicin was repeatedly stopped by the refusal of the patient or toxicity than in the placebo group. The capsaicin ointment group had significantly (statistically significant) greater pain relief (P = .01) after the first 8 weeks, with an average pain reduction of 53% compared to 17%. After completing the 16-week study, patients were asked which treatment period was the most profijtelkjik. Of the responders 60% chose the capsaicin period, 18% chose the placebo period and 22% chose no period (P = .001).
CONCLUSION: An external capsaicin cream reduces postoperative pain and nerve despite some side effects, this capsaicin ointment three times more often preferred by patients over the placebo ointment.
Publication Types:
Clinical Trial
Clinical Trial, Phase III
Randomized Controlled Trial
PMID: 9256142 [PubMed - indexed for MEDLINE]
J Clin Oncol. August 1997, 15 (8) :2974-80
Phase III placebo-controlled trial of capsaicin cream in the Surgical Management of neuropathic pain in cancer patients.
Ellison N, Loprinzi CL, Kugler J, Hatfield AK, Miser A, Sloan JA, Wender DB, Rowland KM, Molina R, Cascino TL, Vukov AM, Dhaliwal HS, Ghosh C.
Geisinger Clinical Oncology Program, Danville, PA, USA.
PURPOSE: A minority of cancer survivors initially develop long-term post Surgical neuropathic pain. That evidence based on capsaicin, the pungent ingredient in hot chili peppers, Might Be Useful for treating neuropathic pain, we Developed the present clinical trial.
PATIENT AND METHODS: Ninety-nine assessable patiënten with neuropathic pain Were Entered Post Surgical failure this study. After stratification, patiënten Were to receive 8 weeks of a 0.075% capsaicin cream followed by 8 weeks or other Appear Identical placebo cream, or vice versa. A capsaicin / placebo cream was to be Applied to the painful site four times daily. Treatment evaluation was Performed by patient-completed weekly questionnaires.
RESULTS: During the first 8-week study period, the capsaicin-cream arm was associated with Substantially more skin burning, skin Redness, and Coughing (P <.0001 for each). Nonetheless, treatment was stopped for toxicity or patient Refusal patiënten Were Just As Often while receiving the placebo as compared with the capsaicin. The capsaicin cream Substantially arm had more pain relief (P = .01) after the first 8 weeks, with an average pain reduction of 53% versus 17%. On completion of the 16-week study period, Which Patients Were Asked treatment period was beneficial musts. Of the responding patients, 60% chose the capsaicin arm, 18% chose the placebo, and 22% chose Neither (P = .001).
CONCLUSION: A topical capsaicin cream decreases post Surgical neuropathic pain and, despite some toxicities, is preferred by a patient by a placebothree-to-one margin among Those expressing a preference.
Publication Types:
Clinical Trial
Clinical Trial, Phase III
Randomized Controlled Trial
PMID: 9256142 [PubMed - indexed for MEDLINE]
