effectiveness of chemo. This enables Jessica van der Bol in her thesis. Article update 8 August 2011
August 4, 2011: source: press release Erasmus Medisch Centrum
Who would smoke during chemotherapy remains the effect of chemo (irinitocan) greatly reduce by as much as 40%. This enables Jessica van der Bol in her thesis with her promotion. Here the press release on this thesis that you can fully understand if you link here:
Smoke hampers effect chemotherapy
People with cancer who smoke, thereby damaging the positive effect of the chemotherapy possible that they follow. Has that Jessica van der Bol of the Erasmus MC researcher.
Transposition
Of different substances in cigarette smoke are known to influence the constituents of a chemo treatment. The tobacco substances have effects on the transposition of the chemo-ingredients in the body.Exposure
Jessica van der Bol investigated at the Department of Internal Oncology of the Erasmus MC 190 patients, both smokers and non-smokers. All these people followed a chemotherapy with the constituent irinotecan smokers bleaching a much lower exposure to the active substance, SN-38 in their blood. The difference with the non-smokers amounted to a whopping 40%.
Side Effects
The smokers were also to have less load of a particular side effect, namely a shortage of white blood cells. This suggests that the chemo treatment to them probably not as powerful worked.
Failure therapy
Van der Bol concludes that patients who smoke during their treatment a possible increased risk on the failure of chemotherapy, because in their body to irinotecan is quickly aborted. Irinotecan know patients under the brand name Campto
Little known
To the treatment for each individual patient has up to succeed, Van der Bol in her thesis developed a new dosing formula for irinotecan.
Remarkably little is known about the effects of smoking on the success of cancer treatments. This is important for many people: more than one in three cancer patients smoke.
