Kanker-actueel Nutrition and supplementation: primary liver tumors of 3 cm. or smaller injected with acetic acid gives significant longer 1 and 2 year survival than injected with ethanol (alcohol) randomised study shows liver below 60

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Nutrition and nutrients: primary liver tumors of 3 cm. or smaller injected with acetic acid gives significant longer 1 and 2 year survival than injected with ethanol (alcohol) randomised study shows patients under 60 and al leverkanker published in 1998. Article update 16 October 2011

Nutrition and nutrients and effect on liver tumors: a Chinese herb-jia wei si jun zi tang-next to an intervention by bv. TACE, LITT, liver perfusion or operation in liver tumors, improves significantly better functioning and recovery of the liver after surgery compared with pure Western approach and guidance of a surgery in liver tumors. Article update 16 October 2011.

Nutrition and nutrients: daily single cups of coffee for 50% risk of primary liver cancer can occur, according to a study among about 100,000 Japanese period of ten years.

nutrition and certain amino acids to patients undergoing liver series operation or liver perfusion, shortens significantly the TACE-LITT-undergone ligduur in the hospital and significantly reduces complications and any infection and ensures faster recovery of the liver functions. Article update 16 October 2011

Nutrition and nutrients and effect on liver cancer: Menatetrenone (= analog in vitamin K2) reduces the chances of a relapse in operable rectal liver cancer significant-42.7% after 1 year and 27.3% after 3 years) and 3 year survival with 23% improves. New meta-analysis confirms results. Article update 15 October 2011

Nutrition and nutrients: daily single cups of coffee for 50% risk of primary liver cancer can occur, thus two long-term prospective studies under ca. 65,000 people. article update 16 October 2011

Nutrition and nutrients: primary liver tumors of 3 cm. or smaller injected with acetic acid gives significant longer 1 and 2 year survival than injected with ethanol (alcohol) randomised study shows patients under 60 and al leverkanker published in 1998. Article update 16 October 2011

May 23, 2005: source: Hepatology. 1998 Jan; 27 (1): 67-72.

Primary liver tumors of 3 cm. or smaller injected with acetic acid gives significant longer 1 and 2 year survival than injected with ethanol (alcohol) randomised study shows patients under 60 and al leverkanker published in 1998. 8% of the 38 tumors injected with acetic acid and 37% of the 35 tumors injected with alcohol showed a local relapse (P< .001)="" gedurende="" een="" follow-up="" periode="" van="" 29="" +/-="" 8="" months="" en="" 23="" +/-="" 10="" months,="" respectievelijk.="" de="" 1-="" en="" 2-jaars="" overleving="" was="" 100%="" en="" 92%="" bij="" azijnzuur="" injecties="" en="" 83%="" en="" 63%="" na="" ethanol="" injecties="" (p=".0017).Dit" is="" een="" significant="" positief="" verschil="" voor="" de="" azijnzuurgroep="" en="" de="" onderzoekers="" stellen="" dan="" ook="" dat="" azijnzuur="" injecties="" superieur="" zijn="" aan="" ethanol="" injecties="" voor="" behandeling="" van="" kleinere="">

Prospective randomized controlled trial comparing percutaneous acetic acid injection and percutaneous ethanol injection for hepatocellular carcinoma, small.

K H, Ito S, Ohnishi, K. Yoshioka Fujiwara
Third Department of Medicine, Saitama Medical School, Japan.

To assess whether ultrasound guided percutaneous acetic acid injection is superior to percutaneous ethanol injection in the treatment of hepatocellular carcinoma (HCC), 60 small patients with one to four HCCs smaller than 3 cm were entered onto a randomized controlled trial. Thirty-one and 29 patients, respectively, were treated by percutaneous acetic acid injection using 50% acetic acid or by percutaneous ethanol injection using absolute ethanol. There were no significant differences in age, sex ratio, Child-Pugh class, size, or number of tumors or tumors between the two groups. When there was no evidence or viable HCC from biopsy, plain and helical dynamic computed tomography angiography, the treatment was considered, or successful and was discontinued. All original tumors were treated successfully by either therapy. However, 8% or 38 tumors treated with percutaneous acetic acid injection and 37% treated with percutaneous ethanol injection or 35 tumors developed a local recurrence (P< .001)="" during="" the="" follow-up="" periods="" of="" 29="" +/-="" 8="" months="" and="" 23="" +/-="" 10="" months,="" respectively.="" the="" 1-="" and="" 2-year="" survival="" rates="" were="" 100%="" and="" 92%="" in="" percutaneous="" acetic="" acid="" injection="" and="" 83%="" and="" 63%="" in="" percutaneous="" ethanol="" injection="" (p=".0017)." a="" multivariate="" analysis="" of="" prognostic="" factors="" revealed="" that="" treatment="" was="" an="" independent="" predictor="" of="" survival.="" the="" risk="" ratio="" of="" percutaneous="" acetic="" acid="" injection="" versus="" percutaneous="" ethanol="" injection="" was="" 0.120="" (range,="" 0.027-0.528;="" p=".0050)." in="" conclusion,="" percutaneous="" acetic="" acid="" injection="" is="" superior="" to="" percutaneous="" ethanol="" injection="" in="" the="" treatment="" of="" small="">

Publication Types:
Clinical Trial
Duplicate Publication
Randomized Controlled Trial

PMID: 9425919 [PubMed-indexed for MEDLINE]